Online Archive of University of Virginia Scholarship
Image Segmentation and Co-Registration in an Intraoperative Multimodal Imaging System (IMIS)1210 views
Author
Papireddy, Anoosha Reddy, Electrical Engineering - School of Engineering and Applied Science, University of Virginia
Advisors
Williams, Mark, Department of Radiology, University of Virginia
Abstract
In this thesis, a new method for segmentation and co-registration of images from multiple modalities is presented. This approach has been tailored to meet the requirements of the Intra-operative Multimodal Imaging System (IMIS) being developed by Dr Mark Williams' lab in the department of Radiology and Medical Imaging at the University of Virginia. The IMIS can be used in a number of applications such as determining the location of primary and secondary carcinomas and sentinel lymph node biopsy. It consists of three imaging modalities- visible, near infrared fluorescence (NIRf), and gamma. The goal of my work is to segment the gamma images and co-register the gamma images with the visible and NIRf images. A series of filtering, binary morphology, edge detection, and active contour based techniques have been used for gamma image segmentation. Image co-registration is achieved with the help of two Attitude and Heading Reference System (AHRS) units.
This method has been tested in phantom studies and other laboratory settings and has shown promising results. Plans for small animal imaging and clinical trials in the operation room setting are underway.
Degree
MS (Master of Science)
Language
English
Rights
All rights reserved (no additional license for public reuse)
Papireddy, Anoosha Reddy. Image Segmentation and Co-Registration in an Intraoperative Multimodal Imaging System (IMIS). University of Virginia, Electrical Engineering - School of Engineering and Applied Science, MS (Master of Science), 2013-05-13, https://doi.org/10.18130/V3B36Q.
