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Dysregulated Innate Immune Signaling as a Driver of Impaired Neurodevelopment225 views
Author
Lammert, Catherine, Neuroscience - School of Medicine, University of Virginia
Advisors
Lukens, John, MD-NESC Neuroscience Medicine Graduate, University of Virginia
Abstract
This thesis is the cumulation of my studies into how the innate immune system affects neurodevelopment. Throughout my graduate career, I have investigated both how lack of innate immune signaling and how overactive immune signaling are detrimental to neurodevelopment. As with most biological systems, neurodevelopment requires a careful balance of immune signaling in order to establish and maintain properly formed connections and functions.
Degree
PHD (Doctor of Philosophy)
Keywords
Inflammasome; Neurodevelopment
Language
English
Rights
All rights reserved (no additional license for public reuse)
Lammert, Catherine. Dysregulated Innate Immune Signaling as a Driver of Impaired Neurodevelopment. University of Virginia, Neuroscience - School of Medicine, PHD (Doctor of Philosophy), 2020-11-28, https://doi.org/10.18130/v3-fxgn-0r63.
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Innate Immune Dysfunction as a driver of impaired neurodevelopment
