Online Archive of University of Virginia Scholarship
Sigma-1 receptor and the control of inflammation
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Author
Rosen, Dorian, Pharmacology - School of Medicine, University of Virginia
0000-0002-0342-8454
Advisors
Gaultier, Alban
, MD-NESC Neuroscience
, University of Virginia
Abstract
The endoplasmic reticulum resident protein sigma-1 receptor is druggable and controls inflammatory outcomes during acute inflammatory insults.
Degree
PHD (Doctor of Philosophy)
Keywords
endoplasmic reticulum; sigma-1 receptor; inflammation; LPS; sepsis; multiple sclerosis; lipopolysaccharide; fecal induced peritonitis; fluvoxamine; XBP1; IRE1
Language
English
Rights
Attribution 4.0 International (CC BY)
Issued Date
2019-05-01
Persistent Link
https://doi.org/10.18130/v3-v131-sy80
Suggested Citation
Rosen, Dorian. Sigma-1 receptor and the control of inflammation. University of Virginia, Pharmacology - School of Medicine, PHD (Doctor of Philosophy), 2019-05-01, https://doi.org/10.18130/v3-v131-sy80.
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