Online Archive of University of Virginia Scholarship
Metabolic and Respiratory Control of Absence Epilepsy236 views
Author
Salvati, Kathryn, Neuroscience - School of Medicine, University of Virginia0000-0002-9557-9259
Advisors
Beenhakker, Mark, MD-PHAR Pharmacology, University of Virginia
Abstract
Absence epilepsy is a pediatric seizure disorder characterized by brief, stereotyped electrographic patterns that often rapidly spread across the brain. Decades of work demonstrate that absence seizures arise from paroxysmal activity within neural networks connecting the thalamus and cortex. How these seizures spontaneously occur remains unknown. Herein, I provide evidence to advance the argument that absence seizures are not simply random events, but are, in fact, events that emerge following disruptions in metabolism and respiration.
Salvati, Kathryn. Metabolic and Respiratory Control of Absence Epilepsy. University of Virginia, Neuroscience - School of Medicine, PHD (Doctor of Philosophy), 2021-11-19, https://doi.org/10.18130/6ksv-ds04.
