Online Archive of University of Virginia Scholarship
Increasing Sepsis Bundle Utilization in the Inpatient Setting218 views
Author
Wright, Aatika, Nursing Practice - School of Nursing, University of Virginia0009-0002-8586-6614
Advisors
Smith, Shelly , Nursing, University of Virginia
Abstract
Background: Sepsis is a life-threatening condition caused by a dysregulated host response to infection, leading to high mortality and significant healthcare costs. While early intervention through SEP-1 bundle components improves outcomes, adherence remains inconsistent due to delayed recognition, evolving criteria, and documentation challenges.
Purpose: This evidence-based practice project aimed to increase sepsis bundle utilization in an inpatient setting by promoting early recognition and consistent protocol adherence.
Methods: Guided by the Iowa Model of Evidence-Based Practice, a standardized sepsis order set was implemented and activated based on SIRS or sepsis criteria. Predictive analytics and timer tools within the EHR supported timely interventions. Data was tracked to assess compliance with bundle elements, including lactate measurement, antibiotic timing, and length of stay. Provider education and engagement campaigns were conducted.
Results: Bundle utilization improved when sepsis was identified early, along with better documentation and awareness aligning with national SEP-1 quality measures.
Conclusions: Standardizing protocols, leveraging predictive tools, and ongoing provider engagement helped improve SEP-1 adherence. Sustained improvement requires leadership support, continued training, and workflow integration.
Degree
DNP (Doctor of Nursing Practice)
Keywords
SEP-1 Compliance; Sepsis; Bundle Adherence; Evidence-Based Practice
Wright, Aatika. Increasing Sepsis Bundle Utilization in the Inpatient Setting. University of Virginia, Nursing Practice - School of Nursing, DNP (Doctor of Nursing Practice), 2025-04-24, https://doi.org/10.18130/20nc-mt18.