Online Archive of University of Virginia Scholarship
A Novel Role for Signal Transducer and Activator of Transcription 5b (STAT5b) in b1 Integrin-Medicated Breast Cancer Cell Migration427 views
Author
Bernaciak, Teresa Marie, Department of Microbiology, University of Virginia
Advisors
Silva, Corinne, Department of Microbiology, University of Virginia
Parsons, Sally, Department of Microbiology, University of Virginia
Parsons, Tom, Department of Microbiology, University of Virginia
Brautigan, David, Department of Microbiology, University of Virginia
Mayo, Marty, Department of Biochemistry and Molecular Genetics, University of Virginia
Guise, Theresa
Abstract
Signal transducer and activator of transcription Sb (STAT5b) is a transcription factor which promotes growth and survival of a number of cancers, including breast cancer. Additionally, STAT5b has been implicated in the invasion of metastatic prostate cancer cells. However, its requirement for breast cancer cell migration and invasion has not been determined. The objective of this work was to determine whether there is a role for STAT5b in breast cancer cell migration.
Note: Abstract extracted from PDF file via OCR
Degree
PHD (Doctor of Philosophy)
Language
English
Rights
All rights reserved (no additional license for public reuse)
Bernaciak, Teresa Marie. A Novel Role for Signal Transducer and Activator of Transcription 5b (STAT5b) in b1 Integrin-Medicated Breast Cancer Cell Migration. University of Virginia, Department of Microbiology, PHD (Doctor of Philosophy), 2009-08-01, https://doi.org/10.18130/V3B538.
