Mass Spectrometry of Immunologically Relevant Molecules
Norris, Andrew, Department of Chemistry, University of Virginia
Hunt, Donald, Department of Chemistry, University of Virginia
Cafiso, David, Department of Chemistry, University of Virginia
Mass spectrometry is a versatile tool which can provide information about the structure of a variety of different molecules from volatile organic molecules to large proteins. The application of mass spectrometry to biologically active molecules has allowed for increased understanding of the structure of these molecules and their functions, and has helped elucidate important features not apparent from genomic data, such as post translational modifications. This thesis presents data from mass spectrometry studies into immunology relevant samples produced by the MHC class I system.
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PHD (Doctor of Philosophy)
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